45 results
Service evaluation of an embedded Early Intervention in Psychosis programme
- Paula Connolly, Cornelia Carey, John Staunton, Bridget Harney, Liah Chambers, Ana-Maria Clarke, Patrick McLaughlin, Kathy Kerins, Katrina Kearney, Peter Whitty
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- Journal:
- Irish Journal of Psychological Medicine , First View
- Published online by Cambridge University Press:
- 02 February 2024, pp. 1-5
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Background:
An average of 1300 adults develop First Episode Psychosis (FEP) in Ireland each year. Early Intervention in Psychosis (EIP) is now widely accepted as best practice in the treatment of conditions such as schizophrenia. A local EIP programme was established in the Dublin South Central Mental Health Service in 2012.
Methods:This is a cross-sectional study of service users presenting to the Dublin South Central Mental Health Service with FEP from 2016 to 2022 following the introduction of the EIP programme. We compared this to a previously published retrospective study of treatment as usual from 2002 to 2012.
Results:Most service users in this study were male, single, unemployed and living with their partner or spouse across both time periods. Cognitive Behavioural Therapy for psychosis was provided to 12% (n = 8) of service users pre-EIP as compared to 52% (n = 30) post-programme introduction (p < 0.001), and 3% (n = 2) of service users engaged with behavioural family therapy pre-EIP as opposed to 15% (n = 9) after (p < 0.01). Rates of composite baseline physical healthcare monitoring improved significantly (p < 0.001).
Conclusion:Exclusive allocation of multidisciplinary team staff to EIP leads to improved compliance with recommended guidelines, particularly CBT-p, formal family therapy and physical health monitoring.
Subsurface scientific exploration of extraterrestrial environments (MINAR 5): analogue science, technology and education in the Boulby Mine, UK – CORRIGENDUM
- Charles S. Cockell, John Holt, Jim Campbell, Harrison Groseman, Jean-Luc Josset, Tomaso R. R. Bontognali, Audra Phelps, Lilit Hakobyan, Libby Kuretn, Annalea Beattie, Jen Blank, Rosalba Bonaccorsi, Christopher McKay, Anushree Shirvastava, Carol Stoker, David Willson, Scott McLaughlin, Sam Payler, Adam Stevens, Jennifer Wadsworth, Loredana Bessone, Matthias Maurer, Francesco Sauro, Javier Martin-Torres, Maria-Paz Zorzano, Anshuman Bhardwaj, Alvaro Soria-Salinas, Thasshwin Mathanlal, Miracle Israel Nazarious, Abhilash Vakkada Ramachandran, Parag Vaishampayan, Lisa Guan, Scott M. Perl, Jon Telling, Ian M. Boothroyd, Ollie Tyson, James Realff, Joseph Rowbottom, Boris Laurent, Matt Gunn, Shaily Shah, Srijan Singh, Sean Paling, Tom Edwards, Louise Yeoman, Emma Meehan, Christopher Toth, Paul Scovell, Barbara Suckling
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- Journal:
- International Journal of Astrobiology / Volume 23 / 2024
- Published online by Cambridge University Press:
- 06 November 2023, e2
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Visualising St Brendan’s: mapping a conservation management plan for Birr Community School
- Gary A. Boyd, Aoibheann Ní Mhearáin, John McLaughlin, Tara Kennedy
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- arq: Architectural Research Quarterly / Volume 26 / Issue 4 / December 2022
- Published online by Cambridge University Press:
- 17 March 2023, pp. 357-376
- Print publication:
- December 2022
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Paradigmatic of a cultural shift in Irish education in the 1960s, St Brendan’s Community School in Birr, County Offaly was designed by Peter and Mary Doyle as a flexible and extendable mat-building articulated by generous social spaces including exterior courtyards and an interior ‘street’. Owned by the Department of Education and Skills, administered by a Board of Management and occupied by approximately one thousand staff and pupils daily, St Brendan’s has been in continuous use since its opening in 1980. Generations of students have benefited from the intimate relationship between the cultural and social life of the school and the architectural form, fabric, and technology that facilitates it. But by the beginning of the twentieth-first century, due to the lack of consideration given to such aspects at the time it was conceived and constructed, the building was suffering from ongoing material degradation and issues in environmental performance.
This article reflects on a research project undertaken on the school, which aimed to provide the means by which its learning environment and energy use could be improved and optimised in a manner consistent with the integrity of the architects’ conceptual thinking and built design: the opportunity for St Brendan’s to continue its course as a successful paradigm, this time for twenty-first-century education through the reconciliation of its future use with its social and education heritage. Guided by the ‘three dimensions of modernity’ - social, technical, and aesthetic - this process involved the development of new ‘ways of seeing’ and ‘methods of action’ applied to the school realised through the production of a series of representations that collectively identified, mapped, and re-presented the significances and values of the school, element by element. The relationships between these phenomena were complex and necessitated an innovative interdisciplinary approach.
St Brendan’s may have embodied a radical new social agenda for education and indeed society in twentieth-century Ireland in its architecture, but the building remains unlisted and, until recently, its significance (nationally and internationally) has been much overlooked. Part of this project’s agenda, therefore, involved raising awareness in the value of the building among existing and potential future stakeholders. The creation of accessible forms of communication that would both synthesise and make clear the complex data generated and the relationships between them was of central importance to the team’s approach. The paper ultimately argues that while attuned to a specific site, these techniques contain the possibility of a wider application, a new visual literacy for the conservation of twentieth-century buildings.
Reducing the Pressure on Mental Health Team by Improving Post-Discharge Follow-Up of Self-Harm or Suicidal Patients in Primary Care
- Nafiz Imtiaz, John McLaughlin
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- Journal:
- BJPsych Open / Volume 8 / Issue S1 / June 2022
- Published online by Cambridge University Press:
- 20 June 2022, p. S99
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Aims
Northern Ireland has had the highest suicide and self-harm rate in the UK since 2012 according to National Statistics Office with 12.5 deaths per 100,000 population compared to 10.5 in the rest of the country. Evidence shows that the risk of suicide hugely increases following self-harm, and the greatest risk is immediately after the self-harm episode. Better access to health care, especially to primary care, in this period, can actively reduce the risk to this vulnerable patient group. Patients assessed for self-harm in the emergency department are often followed up by the mental health/crisis team. Due to lack of resources and staff shortages this is often not possible in a timely fashion. NICE suggests that patients should be offered a follow-up appointment in primary care within 48 hours of discharge. We aimed to ensure 70% of patients discharged from secondary care following an episode of suicidal ideation or self-harm are contacted proactively by mental health practitioner (MHP) or GP within 48 hours of communication from secondary care.
MethodsThe project underwent two PDSA cycles. An electronic workflow was created to provide easy patient identification, assessment and follow-up. A process mapping was done after discussion with the GPs, administrative team, practice nurses and MHP. Outcome was measured by finding out percentage of patients: 1) Contacted within 48 hours of communication following an episode of self-harm 2) Appropriately coded 3) Comprehensively assessed 4) Risk stratified and minimized following each cycle.
ResultsOver a period of three months, following two PDSA cycles, the frequency of these contacts increased from 0 to 80% (median) with an average 3.8 (83%) patients reviewed per week. The patient experience and satisfaction also improved significantly.
ConclusionGeneral practice (GP) has long been known as the next of kin for patients in the health care system. As GP is mostly the first point of contact for the patients, it can contribute significantly to ease the rising pressure on the mental health team. Also, a small number of weekly contacts from each GP can make a huge difference in nationwide patient safety and experience. We hope this intervention will significantly improve patient safety and reduce further self-harm presentation to ED in the long run.
Prediagnostic consumption of vitamin D, calcium and dairy products and colorectal cancer survival: results from the Newfoundland Colorectal Cancer Registry Cohort Study
- Yun Zhu, Jing Zhao, Jillian Vallis, Fuyan Shi, Jennifer R. Woodrow, Yujia Kong, Guangju Zhai, Patrick Parfrey, John R. Mclaughlin, Peizhong Peter Wang
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- Journal:
- British Journal of Nutrition / Volume 128 / Issue 2 / 28 July 2022
- Published online by Cambridge University Press:
- 26 August 2021, pp. 290-299
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- 28 July 2022
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Vitamin D, Ca and dairy products are negatively associated with colorectal cancer (CRC) incidence, but little is known of their influence on CRC survival. To investigate prediagnostic intakes of vitamin D, Ca and dairy products for their relevance to CRC prognosis, we analysed 504 CRC patients enrolled in the Newfoundland Colorectal Cancer Registry Cohort Study who were diagnosed for the first time with CRC between 1999 and 2003. Follow-up for mortality and cancer recurrence was through April 2010. Data on diet and lifestyle factors were gathered via a validated, semi-quantitative FFQ and a Personal History Questionnaire. Multivariate Cox models estimated hazard ratios (HR) and 95 % CI for the relationship of prediagnostic intakes of vitamin D, Ca and dairy products with all-cause mortality (overall survival, OS) and disease-free survival (DFS) among CRC patients. We found that prediagnostic Ca intake from foods, but not total Ca intake, was negatively associated with all-cause mortality (HR for Q2 v. Q1, 0·44; 95 % CI, 0·26, 0·75). An inverse relationship was also seen in a dose–response fashion for prediagnostic cheese intake (HR for Q4 v. Q1, 0·57, 95 % CI, 0·34, 0·95, P trend = 0·029). No evidence for modification by sex, physical activity, alcohol drinking and cigarette smoking was observed. In summary, high prediagnostic intakes of cheese and Ca from foods may be associated with increased survival among CRC patients. By manipulating diet, this study may contribute to the development of novel therapies that add to the armamentarium against CRC. Replication studies are required before any nutritional interventions are made available.
Series Editors’ Preface
- Neil McLaughlin, McMaster University, Ontario
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- Book:
- Erich Fromm and Global Public Sociology
- Published by:
- Bristol University Press
- Published online:
- 21 April 2023
- Print publication:
- 19 July 2021, pp x-xiv
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Summary
Sociology is a highly reflexive subject. All scholarly disciplines examine themselves reflexively in terms of theory and practice as they apply what the sociologist of science Robert Merton once called ‘organised scepticism’. Sociology adds to this constant internal academic debate a forceful, almost obsessive, concern about its very purpose and rationale. This attentiveness to founding principles shows itself in significant intellectual interest in the ‘canon’ of great thinkers and its history as a discipline, in vigorous debate about the boundaries of the discipline, and in considerable inventiveness in developing new areas and subfields of sociology. This fascination with the purpose and social organization of the discipline also reflects in the debate about sociology's civic engagements and commitments, its level of activism, and its moral and political purposes.
This echoes the contemporary discussion about the idea of public sociology. Public sociology is a new phrase for a long-standing debate about the purpose of sociology that began with the discipline's origins. It is therefore no coincidence that students in the twentyfirst century, when being introduced to sociology for the first time, wrestle with ideas formulated centuries before, for while social change has rendered some of these ideas redundant, particularly the Social Darwinism of the nineteenth century and functionalism in the 1950s, familiarity with these earlier debates and frameworks is the lens into understanding the purpose, value and prospect of sociology as key thinkers conceived it in the past. The ideas may have changed but the moral purpose has not.
A contentious discipline is destined to argue continually about its past. Some see the roots of sociology grounded in medieval scholasticism, in eighteenth-century Scotland, with the Scottish Enlightenment's engagement with the social changes wrought by commercialism, in conservative reactions to the Enlightenment, or in nineteenthcentury encounters with the negative effects of industrialization and modernization. Contentious disciplines however, are condemned to always live in their past if they do not also develop a vision for their future; a sense purpose and a rationale that takes the discipline forward. Sociology has always been forward looking, offering an analysis and diagnosis of what C. Wright Mills liked to call the human condition. Interest in the social condition and in its improvement and betterment for the majority of ordinary men and women, has always been sociology's ultimate objective.
Series Editors’ Preface
- Mark Carrigan, Lambros Fatsis, University of Brighton
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- Book:
- The Public and their Platforms
- Published by:
- Bristol University Press
- Published online:
- 05 January 2022
- Print publication:
- 09 June 2021, pp vii-xii
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Summary
Sociology is a highly reflexive subject. All scholarly disciplines examine themselves reflexively in terms of theory and practice as they apply what the sociologist of science Robert Merton once called ‘organised scepticism’. Sociology adds to this constant internal academic debate also a vigorous, almost obsessive, concern about its very purpose and rationale. This attentiveness to founding principles shows itself in significant intellectual interest in the ‘canon’ of great thinkers and its history as a discipline, in vigorous debate about the boundaries of the discipline, and in considerable inventiveness in developing new areas and subfields of sociology. This fascination with the purpose and social organization of the discipline also reflects in the debate about sociology's civic engagements and commitments, its level of activism, and its moral and political purposes.
This echoes the contemporary discussion about the idea of public sociology. ‘Public sociology’ is a new phrase for a long-standing debate about the purpose of sociology that began with the discipline's origins. It is therefore no coincidence that students in the 21st century, when being introduced to sociology for the first time, wrestle with ideas formulated centuries before, for while social change has rendered some of these ideas redundant, particularly the Social Darwinism of the 19th century and functionalism in the 1950s, familiarity with these earlier debates and frameworks is the lens into understanding the purpose, value and prospect of sociology as key thinkers conceived it in the past. The ideas may have changed but the moral purpose has not.
A contentious discipline is destined to argue continually about its past. Some see the roots of sociology grounded in medieval scholasticism, in 18th century Scotland, with the Scottish Enlightenment's engagement with the social changes wrought by commercialism, in conservative reactions to the Enlightenment or in 19th century encounters with the negative effects of industrialization and modernization. Contentious disciplines, however, are condemned to always live in their past if they do not also develop a vision for their future; a sense purpose and a rationale that takes the discipline forward. Sociology has always been forward looking, offering an analysis and diagnosis of what C. Wright Mills liked to call the human condition.
Identifying intervention strategies for preventing the mental health consequences of childhood adversity: A modified Delphi study
- Leslie R. Rith-Najarian, Noah S. Triplett, John R. Weisz, Katie A. McLaughlin
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- Journal:
- Development and Psychopathology / Volume 33 / Issue 2 / May 2021
- Published online by Cambridge University Press:
- 06 May 2021, pp. 748-765
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Exposure to childhood adversity is a powerful risk factor for psychopathology. Despite extensive efforts, we have not yet identified effective or scalable interventions that prevent the emergence of mental health problems in children who have experienced adversity. In this modified Delphi study, we identified intervention strategies for effectively targeting both the neurodevelopmental mechanisms linking childhood adversity and psychopathology – including heightened emotional reactivity, difficulties with emotion regulation, blunted reward processing, and social information processing biases, as well as a range of psychopathology symptoms. We iteratively synthesized information from experts in the field and relevant meta-analyses through three surveys, first with experts in intervention development, prevention, and childhood adversity (n = 32), and then within our study team (n = 8). The results produced increasing stability and good consensus on intervention strategy recommendations for specific neurodevelopmental mechanisms and symptom presentations and on strength of evidence ratings of intervention strategies targeting youth and parents. More broadly, our findings highlight how intervention decision making can be informed by meta-analyses, enhanced by aggregate group feedback, saturated before consensus, and persistently subjective or even contradictory. Ultimately, the results converged on several promising intervention strategies for prevention programming with adversity-exposed youth, which will be tested in an upcoming clinical trial.
Series Editors’ Preface
- Edited by Eurig Scandrett, Queen Margaret University, Edinburgh
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- Book:
- Public Sociology as Educational Practice
- Published by:
- Bristol University Press
- Published online:
- 02 March 2021
- Print publication:
- 14 September 2020, pp xvii-xxii
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Summary
Sociology is a highly reflexive subject. All scholarly disciplines examine themselves reflexively in terms of theory and practice as they apply what the sociologist of science Robert Merton once called ‘organised scepticism’. Sociology adds to this constant internal academic debate also a vigorous, almost obsessive, concern about its very purpose and rationale. This attentiveness to founding principles shows itself in significant intellectual interest in the ‘canon’ of great thinkers and its history as a discipline, in vigorous debate about the boundaries of the discipline, and in considerable inventiveness in developing new areas and subfields of sociology. This fascination with the purpose and social organisation of the discipline also reflects in the debate about sociology's civic engagements and commitments, its level of activism, and its moral and political purposes.
This echoes the contemporary discussion about the idea of public sociology. ‘Public sociology’ is a new phrase for a long-standing debate about the purpose of sociology that began with the discipline's origins. It is therefore no coincidence that students in the twentyfirst century, when being introduced to sociology for the first time, wrestle with ideas formulated centuries before, for while social change has rendered some of these ideas redundant, particularly the Social Darwinism of the nineteenth century and functionalism in the 1950s, familiarity with these earlier debates and frameworks is the lens into understanding the purpose, value and prospect of sociology as key thinkers conceived it in the past. The ideas may have changed but the moral purpose has not.
A contentious discipline is destined to argue continually about its past. Some see the roots of sociology grounded in medieval scholasticism, in eighteenth-century Scotland, with the Scottish Enlightenment's engagement with the social changes wrought by commercialism, in conservative reactions to the Enlightenment or in nineteenthcentury encounters with the negative effects of industrialisation and modernisation. Contentious disciplines, however, are condemned to always live in their past if they do not also develop a vision for their future; a sense of purpose and a rationale that takes the discipline forward. Sociology has always been forward looking, offering an analysis and diagnosis of what C. Wright Mills liked to call the human condition.
Appetite, the enteroendocrine system, gastrointestinal disease and obesity
- Benjamin Crooks, Nikoleta S. Stamataki, John T. McLaughlin
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- Journal:
- Proceedings of the Nutrition Society / Volume 80 / Issue 1 / February 2021
- Published online by Cambridge University Press:
- 04 May 2020, pp. 50-58
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The enteroendocrine system is located in the gastrointestinal (GI) tract, and makes up the largest endocrine system in the human body. Despite that, its roles and functions remain incompletely understood. Gut regulatory peptides are the main products of enteroendocrine cells, and play an integral role in the digestion and absorption of nutrients through their effect on intestinal secretions and gut motility. Several peptides, such as cholecystokinin, polypeptide YY and glucagon-like peptide-1, have traditionally been reported to suppress appetite following food intake, so-called satiety hormones. In this review, we propose that, in the healthy individual, this system to regulate appetite does not play a dominant role in normal food intake regulation, and that there is insufficient evidence to wholly link postprandial endogenous gut peptides with appetite-related behaviours. Instead, or additionally, top-down, hedonic drive and neurocognitive factors may have more of an impact on food intake. In GI disease however, supraphysiological levels of these hormones may have more of an impact on appetite regulation as well as contributing to other unpleasant abdominal symptoms, potentially as part of an innate response to injury. Further work is required to better understand the mechanisms involved in appetite control and unlock the therapeutic potential offered by the enteroendocrine system in GI disease and obesity.
2160 Does maternal schistosomiasis affect the humoral and cellular vaccine responses of infants?
- Deborah Bloch, Taryn McLaughlin, Cheryl Day, W. Evan Secor, Govert van Dam, Paul Corstjens, Heather B. Jaspan, Grace John-Stewart, Saad B. Omer, Lisa Cranmer
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- Journal:
- Journal of Clinical and Translational Science / Volume 2 / Issue S1 / June 2018
- Published online by Cambridge University Press:
- 21 November 2018, p. 10
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OBJECTIVES/SPECIFIC AIMS: The aims of this study are 2-fold: (1) to determine if maternal schistosomiasis affects maternal immunity to tetanus and/or transplacental transfer of antitetanus toxoid (TT) immunoglobulin G (IgG) from mother to infant and (2) determine the influence of maternal schistosomiasis on infant BCG vaccine immunogenicity. METHODS/STUDY POPULATION: The study will utilize blood samples from a historic cohort of 100 mother-infant pairs from Kisumu, Kenya, a schistosomiasis-endemic area. For the first aim, we will evaluate maternal schistosomal circulating anodic antigen, which has improved sensitivity and specificity to detect active schistosomiasis from serum, and antisoluble egg antigen IgG positivity compared with quantitative maternal anti-TT IgG at delivery and anti-TT IgG cord blood to maternal blood ratio (cord:maternal ratio). For the second aim, we will evaluate association between maternal schistosomiasis as detected by circulating anodic antigen and antisoluble egg antigen IgG at delivery and infant BCG-specific Th1-cytokine positive CD4+ cells at 10 weeks following BCG vaccination at birth. RESULTS/ANTICIPATED RESULTS: We hypothesize that active maternal schistosomiasis will be associated with decreased maternal anti-TT IgG and reduced efficiency of transplacental transfer, as measured by infant cord blood to maternal blood ratio of anti-TT IgG. We also expect that maternal schistosomiasis will be associated with decreased infant immunogenicity to BCG vaccine. DISCUSSION/SIGNIFICANCE OF IMPACT: This is a formative study on infant vaccine immunity using laboratory methodology not previously applied. Understanding infant immunity in the setting of maternal schistosomiasis will inform vaccination strategies and tailor vaccine development in schistosome-endemic areas such as Kenya, where neither TB nor neonatal tetanus have been eradicated. Additionally, our results will inform public health policies to consider integration of antischistosomal agents in antenatal care.
Subsurface scientific exploration of extraterrestrial environments (MINAR 5): analogue science, technology and education in the Boulby Mine, UK
- Charles S. Cockell, John Holt, Jim Campbell, Harrison Groseman, Jean-Luc Josset, Tomaso R. R. Bontognali, Audra Phelps, Lilit Hakobyan, Libby Kuretn, Annalea Beattie, Jen Blank, Rosalba Bonaccorsi, Christopher McKay, Anushree Shirvastava, Carol Stoker, David Willson, Scott McLaughlin, Sam Payler, Adam Stevens, Jennifer Wadsworth, Loredana Bessone, Matthias Maurer, Francesco Sauro, Javier Martin-Torres, Maria-Paz Zorzano, Anshuman Bhardwaj, Alvaro Soria-Salinas, Thasshwin Mathanlal, Miracle Israel Nazarious, Abhilash Vakkada Ramachandran, Parag Vaishampayan, Lisa Guan, Scott M. Perl, Jon Telling, Ian M. Boothroyd, Ollie Tyson, James Realff, Joseph Rowbottom, Boris Laurent, Matt Gunn, Shaily Shah, Srijan Singh, Sean Paling, Tom Edwards, Louise Yeoman, Emma Meehan, Christopher Toth, Paul Scovell, Barbara Suckling
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- Journal:
- International Journal of Astrobiology / Volume 18 / Issue 2 / April 2019
- Published online by Cambridge University Press:
- 02 July 2018, pp. 157-182
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The deep subsurface of other planetary bodies is of special interest for robotic and human exploration. The subsurface provides access to planetary interior processes, thus yielding insights into planetary formation and evolution. On Mars, the subsurface might harbour the most habitable conditions. In the context of human exploration, the subsurface can provide refugia for habitation from extreme surface conditions. We describe the fifth Mine Analogue Research (MINAR 5) programme at 1 km depth in the Boulby Mine, UK in collaboration with Spaceward Bound NASA and the Kalam Centre, India, to test instruments and methods for the robotic and human exploration of deep environments on the Moon and Mars. The geological context in Permian evaporites provides an analogue to evaporitic materials on other planetary bodies such as Mars. A wide range of sample acquisition instruments (NASA drills, Small Planetary Impulse Tool (SPLIT) robotic hammer, universal sampling bags), analytical instruments (Raman spectroscopy, Close-Up Imager, Minion DNA sequencing technology, methane stable isotope analysis, biomolecule and metabolic life detection instruments) and environmental monitoring equipment (passive air particle sampler, particle detectors and environmental monitoring equipment) was deployed in an integrated campaign. Investigations included studying the geochemical signatures of chloride and sulphate evaporitic minerals, testing methods for life detection and planetary protection around human-tended operations, and investigations on the radiation environment of the deep subsurface. The MINAR analogue activity occurs in an active mine, showing how the development of space exploration technology can be used to contribute to addressing immediate Earth-based challenges. During the campaign, in collaboration with European Space Agency (ESA), MINAR was used for astronaut familiarization with future exploration tools and techniques. The campaign was used to develop primary and secondary school and primary to secondary transition curriculum materials on-site during the campaign which was focused on a classroom extra vehicular activity simulation.
Trauma and psychotic experiences: transnational data from the World Mental Health Survey
- John J. McGrath, Sukanta Saha, Carmen C. W. Lim, Sergio Aguilar-Gaxiola, Jordi Alonso, Laura H. Andrade, Evelyn J. Bromet, Ronny Bruffaerts, José M. Caldas de Almeida, Graça Cardoso, Giovanni de Girolamo, John Fayyad, Silvia Florescu, Oye Gureje, Josep M. Haro, Norito Kawakami, Karestan C. Koenen, Viviane Kovess-Masfety, Sing Lee, Jean-Pierre Lepine, Katie A. McLaughlin, Maria E. Medina-Mora, Fernando Navarro-Mateu, Akin Ojagbemi, Jose Posada-Villa, Nancy Sampson, Kate M. Scott, Hisateru Tachimori, Margreet ten Have, Kenneth S. Kendler, Ronald C. Kessler,
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- Journal:
- The British Journal of Psychiatry / Volume 211 / Issue 6 / December 2017
- Published online by Cambridge University Press:
- 02 January 2018, pp. 373-380
- Print publication:
- December 2017
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Background
Traumatic events are associated with increased risk of psychotic experiences, but it is unclear whether this association is explained by mental disorders prior to psychotic experience onset.
AimsTo investigate the associations between traumatic events and subsequent psychotic experience onset after adjusting for post-traumatic stress disorder and other mental disorders.
MethodWe assessed 29 traumatic event types and psychotic experiences from the World Mental Health surveys and examined the associations of traumatic events with subsequent psychotic experience onset with and without adjustments for mental disorders.
ResultsRespondents with any traumatic events had three times the odds of other respondents of subsequently developing psychotic experiences (OR=3.1, 95% CI 2.7–3.7), with variability in strength of association across traumatic event types. These associations persisted after adjustment for mental disorders.
ConclusionsExposure to traumatic events predicts subsequent onset of psychotic experiences even after adjusting for comorbid mental disorders.
A FORMAL PROOF OF THE KEPLER CONJECTURE
- Part of
- THOMAS HALES, MARK ADAMS, GERTRUD BAUER, TAT DAT DANG, JOHN HARRISON, LE TRUONG HOANG, CEZARY KALISZYK, VICTOR MAGRON, SEAN MCLAUGHLIN, TAT THANG NGUYEN, QUANG TRUONG NGUYEN, TOBIAS NIPKOW, STEVEN OBUA, JOSEPH PLESO, JASON RUTE, ALEXEY SOLOVYEV, THI HOAI AN TA, NAM TRUNG TRAN, THI DIEP TRIEU, JOSEF URBAN, KY VU, ROLAND ZUMKELLER
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- Journal:
- Forum of Mathematics, Pi / Volume 5 / 2017
- Published online by Cambridge University Press:
- 29 May 2017, e2
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This article describes a formal proof of the Kepler conjecture on dense sphere packings in a combination of the HOL Light and Isabelle proof assistants. This paper constitutes the official published account of the now completed Flyspeck project.
Contributors
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- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. Brittan, Justin Broackes, Dan W. Brock, Aaron Bronfman, Jeffrey E. Brower, Bartosz Brozek, Anthony Brueckner, Jeffrey Bub, Lara Buchak, Otavio Bueno, Ann E. Bumpus, Robert W. Burch, John Burgess, Arthur W. Burks, Panayot Butchvarov, Robert E. Butts, Marina Bykova, Patrick Byrne, David Carr, Noël Carroll, Edward S. Casey, Victor Caston, Victor Caston, Albert Casullo, Robert L. Causey, Alan K. L. Chan, Ruth Chang, Deen K. Chatterjee, Andrew Chignell, Roderick M. Chisholm, Kelly J. Clark, E. J. Coffman, Robin Collins, Brian P. Copenhaver, John Corcoran, John Cottingham, Roger Crisp, Frederick J. Crosson, Antonio S. Cua, Phillip D. Cummins, Martin Curd, Adam Cureton, Andrew Cutrofello, Stephen Darwall, Paul Sheldon Davies, Wayne A. Davis, Timothy Joseph Day, Claudio de Almeida, Mario De Caro, Mario De Caro, John Deigh, C. F. Delaney, Daniel C. Dennett, Michael R. DePaul, Michael Detlefsen, Daniel Trent Devereux, Philip E. Devine, John M. Dillon, Martin C. Dillon, Robert DiSalle, Mary Domski, Alan Donagan, Paul Draper, Fred Dretske, Mircea Dumitru, Wilhelm Dupré, Gerald Dworkin, John Earman, Ellery Eells, Catherine Z. Elgin, Berent Enç, Ronald P. Endicott, Edward Erwin, John Etchemendy, C. Stephen Evans, Susan L. Feagin, Solomon Feferman, Richard Feldman, Arthur Fine, Maurice A. Finocchiaro, William FitzPatrick, Richard E. Flathman, Gvozden Flego, Richard Foley, Graeme Forbes, Rainer Forst, Malcolm R. Forster, Daniel Fouke, Patrick Francken, Samuel Freeman, Elizabeth Fricker, Miranda Fricker, Michael Friedman, Michael Fuerstein, Richard A. Fumerton, Alan Gabbey, Pieranna Garavaso, Daniel Garber, Jorge L. A. Garcia, Robert K. Garcia, Don Garrett, Philip Gasper, Gerald Gaus, Berys Gaut, Bernard Gert, Roger F. Gibson, Cody Gilmore, Carl Ginet, Alan H. Goldman, Alvin I. Goldman, Alfonso Gömez-Lobo, Lenn E. Goodman, Robert M. Gordon, Stefan Gosepath, Jorge J. E. Gracia, Daniel W. Graham, George A. Graham, Peter J. Graham, Richard E. Grandy, I. Grattan-Guinness, John Greco, Philip T. Grier, Nicholas Griffin, Nicholas Griffin, David A. Griffiths, Paul J. Griffiths, Stephen R. Grimm, Charles L. Griswold, Charles B. Guignon, Pete A. Y. Gunter, Dimitri Gutas, Gary Gutting, Paul Guyer, Kwame Gyekye, Oscar A. Haac, Raul Hakli, Raul Hakli, Michael Hallett, Edward C. Halper, Jean Hampton, R. James Hankinson, K. R. Hanley, Russell Hardin, Robert M. Harnish, William Harper, David Harrah, Kevin Hart, Ali Hasan, William Hasker, John Haugeland, Roger Hausheer, William Heald, Peter Heath, Richard Heck, John F. Heil, Vincent F. Hendricks, Stephen Hetherington, Francis Heylighen, Kathleen Marie Higgins, Risto Hilpinen, Harold T. Hodes, Joshua Hoffman, Alan Holland, Robert L. Holmes, Richard Holton, Brad W. Hooker, Terence E. Horgan, Tamara Horowitz, Paul Horwich, Vittorio Hösle, Paul Hoβfeld, Daniel Howard-Snyder, Frances Howard-Snyder, Anne Hudson, Deal W. Hudson, Carl A. Huffman, David L. Hull, Patricia Huntington, Thomas Hurka, Paul Hurley, Rosalind Hursthouse, Guillermo Hurtado, Ronald E. Hustwit, Sarah Hutton, Jonathan Jenkins Ichikawa, Harry A. Ide, David Ingram, Philip J. Ivanhoe, Alfred L. Ivry, Frank Jackson, Dale Jacquette, Joseph Jedwab, Richard Jeffrey, David Alan Johnson, Edward Johnson, Mark D. Jordan, Richard Joyce, Hwa Yol Jung, Robert Hillary Kane, Tomis Kapitan, Jacquelyn Ann K. Kegley, James A. Keller, Ralph Kennedy, Sergei Khoruzhii, Jaegwon Kim, Yersu Kim, Nathan L. King, Patricia Kitcher, Peter D. Klein, E. D. Klemke, Virginia Klenk, George L. Kline, Christian Klotz, Simo Knuuttila, Joseph J. Kockelmans, Konstantin Kolenda, Sebastian Tomasz Kołodziejczyk, Isaac Kramnick, Richard Kraut, Fred Kroon, Manfred Kuehn, Steven T. Kuhn, Henry E. Kyburg, John Lachs, Jennifer Lackey, Stephen E. Lahey, Andrea Lavazza, Thomas H. Leahey, Joo Heung Lee, Keith Lehrer, Dorothy Leland, Noah M. Lemos, Ernest LePore, Sarah-Jane Leslie, Isaac Levi, Andrew Levine, Alan E. Lewis, Daniel E. Little, Shu-hsien Liu, Shu-hsien Liu, Alan K. L. Chan, Brian Loar, Lawrence B. Lombard, John Longeway, Dominic McIver Lopes, Michael J. Loux, E. J. Lowe, Steven Luper, Eugene C. Luschei, William G. Lycan, David Lyons, David Macarthur, Danielle Macbeth, Scott MacDonald, Jacob L. Mackey, Louis H. Mackey, Penelope Mackie, Edward H. Madden, Penelope Maddy, G. B. Madison, Bernd Magnus, Pekka Mäkelä, Rudolf A. Makkreel, David Manley, William E. Mann (W.E.M.), Vladimir Marchenkov, Peter Markie, Jean-Pierre Marquis, Ausonio Marras, Mike W. Martin, A. P. Martinich, William L. McBride, David McCabe, Storrs McCall, Hugh J. McCann, Robert N. McCauley, John J. McDermott, Sarah McGrath, Ralph McInerny, Daniel J. McKaughan, Thomas McKay, Michael McKinsey, Brian P. McLaughlin, Ernan McMullin, Anthonie Meijers, Jack W. Meiland, William Jason Melanson, Alfred R. Mele, Joseph R. Mendola, Christopher Menzel, Michael J. Meyer, Christian B. Miller, David W. Miller, Peter Millican, Robert N. Minor, Phillip Mitsis, James A. Montmarquet, Michael S. Moore, Tim Moore, Benjamin Morison, Donald R. Morrison, Stephen J. Morse, Paul K. Moser, Alexander P. D. Mourelatos, Ian Mueller, James Bernard Murphy, Mark C. Murphy, Steven Nadler, Jan Narveson, Alan Nelson, Jerome Neu, Samuel Newlands, Kai Nielsen, Ilkka Niiniluoto, Carlos G. Noreña, Calvin G. Normore, David Fate Norton, Nikolaj Nottelmann, Donald Nute, David S. Oderberg, Steve Odin, Michael O’Rourke, Willard G. Oxtoby, Heinz Paetzold, George S. Pappas, Anthony J. Parel, Lydia Patton, R. P. Peerenboom, Francis Jeffry Pelletier, Adriaan T. Peperzak, Derk Pereboom, Jaroslav Peregrin, Glen Pettigrove, Philip Pettit, Edmund L. Pincoffs, Andrew Pinsent, Robert B. Pippin, Alvin Plantinga, Louis P. Pojman, Richard H. Popkin, John F. Post, Carl J. Posy, William J. Prior, Richard Purtill, Michael Quante, Philip L. Quinn, Philip L. Quinn, Elizabeth S. Radcliffe, Diana Raffman, Gerard Raulet, Stephen L. Read, Andrews Reath, Andrew Reisner, Nicholas Rescher, Henry S. Richardson, Robert C. Richardson, Thomas Ricketts, Wayne D. Riggs, Mark Roberts, Robert C. Roberts, Luke Robinson, Alexander Rosenberg, Gary Rosenkranz, Bernice Glatzer Rosenthal, Adina L. Roskies, William L. Rowe, T. M. Rudavsky, Michael Ruse, Bruce Russell, Lilly-Marlene Russow, Dan Ryder, R. M. Sainsbury, Joseph Salerno, Nathan Salmon, Wesley C. Salmon, Constantine Sandis, David H. Sanford, Marco Santambrogio, David Sapire, Ruth A. Saunders, Geoffrey Sayre-McCord, Charles Sayward, James P. Scanlan, Richard Schacht, Tamar Schapiro, Frederick F. Schmitt, Jerome B. Schneewind, Calvin O. Schrag, Alan D. Schrift, George F. Schumm, Jean-Loup Seban, David N. Sedley, Kenneth Seeskin, Krister Segerberg, Charlene Haddock Seigfried, Dennis M. Senchuk, James F. Sennett, William Lad Sessions, Stewart Shapiro, Tommie Shelby, Donald W. Sherburne, Christopher Shields, Roger A. Shiner, Sydney Shoemaker, Robert K. Shope, Kwong-loi Shun, Wilfried Sieg, A. John Simmons, Robert L. Simon, Marcus G. Singer, Georgette Sinkler, Walter Sinnott-Armstrong, Matti T. Sintonen, Lawrence Sklar, Brian Skyrms, Robert C. Sleigh, Michael Anthony Slote, Hans Sluga, Barry Smith, Michael Smith, Robin Smith, Robert Sokolowski, Robert C. Solomon, Marta Soniewicka, Philip Soper, Ernest Sosa, Nicholas Southwood, Paul Vincent Spade, T. L. S. Sprigge, Eric O. Springsted, George J. Stack, Rebecca Stangl, Jason Stanley, Florian Steinberger, Sören Stenlund, Christopher Stephens, James P. Sterba, Josef Stern, Matthias Steup, M. A. Stewart, Leopold Stubenberg, Edith Dudley Sulla, Frederick Suppe, Jere Paul Surber, David George Sussman, Sigrún Svavarsdóttir, Zeno G. Swijtink, Richard Swinburne, Charles C. Taliaferro, Robert B. Talisse, John Tasioulas, Paul Teller, Larry S. Temkin, Mark Textor, H. S. Thayer, Peter Thielke, Alan Thomas, Amie L. Thomasson, Katherine Thomson-Jones, Joshua C. Thurow, Vzalerie Tiberius, Terrence N. Tice, Paul Tidman, Mark C. Timmons, William Tolhurst, James E. Tomberlin, Rosemarie Tong, Lawrence Torcello, Kelly Trogdon, J. D. Trout, Robert E. Tully, Raimo Tuomela, John Turri, Martin M. Tweedale, Thomas Uebel, Jennifer Uleman, James Van Cleve, Harry van der Linden, Peter van Inwagen, Bryan W. Van Norden, René van Woudenberg, Donald Phillip Verene, Samantha Vice, Thomas Vinci, Donald Wayne Viney, Barbara Von Eckardt, Peter B. M. Vranas, Steven J. Wagner, William J. Wainwright, Paul E. Walker, Robert E. Wall, Craig Walton, Douglas Walton, Eric Watkins, Richard A. Watson, Michael V. Wedin, Rudolph H. Weingartner, Paul Weirich, Paul J. Weithman, Carl Wellman, Howard Wettstein, Samuel C. Wheeler, Stephen A. White, Jennifer Whiting, Edward R. Wierenga, Michael Williams, Fred Wilson, W. Kent Wilson, Kenneth P. Winkler, John F. Wippel, Jan Woleński, Allan B. Wolter, Nicholas P. Wolterstorff, Rega Wood, W. Jay Wood, Paul Woodruff, Alison Wylie, Gideon Yaffe, Takashi Yagisawa, Yutaka Yamamoto, Keith E. Yandell, Xiaomei Yang, Dean Zimmerman, Günter Zoller, Catherine Zuckert, Michael Zuckert, Jack A. Zupko (J.A.Z.)
- Edited by Robert Audi, University of Notre Dame, Indiana
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- The Cambridge Dictionary of Philosophy
- Published online:
- 05 August 2015
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- 27 April 2015, pp ix-xxx
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The “Alzheimer's Type” Profile of Semantic Clustering in Amnestic Mild Cognitive Impairment
- Paula M. McLaughlin, Matthew J. Wright, Michael LaRocca, Peter T. Nguyen, Edmond Teng, Liana G. Apostolova, John M. Ringman, Yan Zhou, Jeffrey L. Cummings, Ellen Woo
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- Journal of the International Neuropsychological Society / Volume 20 / Issue 4 / April 2014
- Published online by Cambridge University Press:
- 13 February 2014, pp. 402-412
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Impairments in learning and recall have been well established in amnestic mild cognitive impairment (aMCI). However, a relative dearth of studies has examined the profiles of memory strategy use in persons with aMCI relative to those with Alzheimer's disease (AD). Participants with aMCI, nonamnestic MCI, AD, and healthy older adults were administered the California Verbal Learning Test-II (CVLT-II). Measures of semantic clustering and recall were obtained across learning and delayed recall trials. In addition, we investigated whether deficits in semantic clustering were related to progression from healthy aging to aMCI and from aMCI to AD. The aMCI group displayed similar semantic clustering performance as the AD participants, whereas the AD group showed greater impairments on recall relative to the aMCI participants. Control participants who progressed to aMCI showed reduced semantic clustering at the short delay at baseline compared to individuals who remained diagnostically stable across follow-up visits. These findings show that the ability to engage in an effective memory strategy is compromised in aMCI, before AD has developed, suggesting that disruptions in semantic networks are an early marker of the disease. (JINS, 2014, 20, 1–11)
Dietary N-nitroso compounds and risk of colorectal cancer: a case–control study in Newfoundland and Labrador and Ontario, Canada
- Yun Zhu, Peizhon Peter Wang, Jing Zhao, Roger Green, Zhuoyu Sun, Barbara Roebothan, Josh Squires, Sharon Buehler, Elizabeth Dicks, Jinhui Zhao, Michelle Cotterchio, Peter T. Campbell, Meera Jain, Patrick S. Parfrey, John R. Mclaughlin
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- Journal:
- British Journal of Nutrition / Volume 111 / Issue 6 / 28 March 2014
- Published online by Cambridge University Press:
- 25 October 2013, pp. 1109-1117
- Print publication:
- 28 March 2014
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Several N-nitroso compounds (NOC) have been shown to be carcinogenic in a variety of laboratory animals, but evidence of their carcinogenicity in humans is lacking. We aimed to examine the association between NOC intake and colorectal cancer (CRC) risk and possible effect modification by vitamins C and E and protein in a large case–control study carried out in Newfoundland and Labrador and Ontario, Canada. A total of 1760 case patients with pathologically confirmed adenocarcinoma and 2481 population controls were asked to complete a self-administered FFQ to evaluate their dietary intakes 1 year before diagnosis (for cases) or interview (for controls). Adjusted OR and 95 % CI were calculated across the quintiles of NOC (measured by N-nitrosodimethylamine (NDMA)) intake and relevant food items using unconditional logistic regression. NDMA intake was found to be associated with a higher risk of CRC (highest v. lowest quintiles: OR 1·42, 95 % CI 1·03, 1·96; P for trend = 0·005), specifically for rectal carcinoma (OR 1·61, 95 % CI 1·11, 2·35; P for trend = 0·01). CRC risk also increased with the consumption of NDMA-containing meats when the highest tertile was compared with the lowest tertile (OR 1·47, 95 % CI 1·03, 2·10; P for trend = 0·20). There was evidence of effect modification between dietary vitamin E and NDMA. Individuals with high NDMA and low vitamin E intakes had a significantly increased risk than those with both low NDMA and low vitamin E intakes (OR 3·01, 95 % CI 1·43, 6·51; P for interaction = 0·017). The present results support the hypothesis that NOC intake may be positively associated with CRC risk in humans. Vitamin E, which inhibits nitrosation, could modify the effect of NDMA on CRC risk.
Contributors
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- By Núria Duran Adroher, Sergio Aguilar-Gaxiola, Jordi Alonso, Ali Obaid Al-Hamzawi, Laura Helena Andrade, Matthias C. Angermeyer, James Anthony, Corina Benjet, Guilherme Borges, Joshua Breslau, Evelyn J. Bromet, Ronny Bruffaerts, Brendan Bunting, Huibert Burger, José Miguel Caldas de Almeida, Graça Cardoso, Somnath Chatterji, Wai Tat Chiu, Giovanni de Girolamo, Ron de Graaf, Peter de Jonge, Koen Demyttenaere, John Fayyad, Alize J. Ferrari, Silvia Florescu, Anne M. Gadermann, Meyer Glantz, Jen Green, Michael J. Gruber, Oye Gureje, Josep Maria Haro, Yanling He, Steven G. Heeringa, Hristo Hinkov, Chiyi Hu, Yueqin Huang, Irving Hwang, Robert Jin, Elie G. Karam, Norito Kawakami, Ronald C. Kessler, Lola Kola, Viviane Kovess-Masféty, Michael C. Lane, Carmen Lara, William LeBlanc, Sing Lee, Jean-Pierre Lépine, Daphna Levinson, Zhaorui Liu, Gustavo Loera, Herbert Marschinger, Katie A. McLaughlin, Maria Elena Medina-Mora, Elizabeth Miller, Samuel D. Murphy, Aimee Nasser Karam, Matthew K. Nock, Mark A. Oakley Browne, Siobhan O’Neill, Johan Ormel, Beth-Ellen Pennell, Maria V. Petukhova, José Posada-Villa, Rajesh Sagar, Mohammad Salih Khalaf, Nancy A. Sampson, Kathleen Saunders, Michael Schoenbaum, Kate M. Scott, Soraya Seedat, Victoria Shahly, Dan J. Stein, Hisateru Tachimori, Nezar Ismet Taib, Adley Tsang, T. Bedirhan Üstün, Maria Carmen Viana, Gemma Vilagut, Michael R. Von Korff, J. Elisabeth Wells, Harvey A. Whiteford, David R. Williams, Ben Wu, Miguel Xavier, Alan M. Zaslavsky
- Edited by Jordi Alonso, Universitat Pompeu Fabra, Barcelona, Somnath Chatterji, World Health Organization, Geneva, Yanling He
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- The Burdens of Mental Disorders
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- 09 May 2013, pp ix-xii
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Ageing and the gut
- Edward Britton, John T. McLaughlin
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- Journal:
- Proceedings of the Nutrition Society / Volume 72 / Issue 1 / February 2013
- Published online by Cambridge University Press:
- 12 November 2012, pp. 173-177
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The goal of this brief review is to address the role of the ageing gut in the genesis of malnutrition in the elderly. We assess the burden of malnutrition in the elderly, exploring the role of comorbid conditions and neurohumoral changes that take place to contribute towards the process of anorexia associated with ageing. Following this, the review assesses physiological changes that occur in each part of the gastrointestinal (GI) tract and what implication they may have in clinical practice. In the oropharynx and the oesophagus, changes in swallowing and oesophageal motility associated with ageing can be demonstrated using physiological testing. However, in the absence of comorbid disease, they often have little, if any, clinical significance. In the stomach, reduced fundal compliance may contribute to early satiety; however, the primary change is hypochlorhydria, which may predispose to malabsorption or bacterial overgrowth further along the GI tract. Almost uniquely, the small bowel, particularly its absorptive function, is unaffected by age and we review the literature demonstrating this. In the colon, there is evidence of a prolonged transit time related to a reduction in both neurotransmitters and receptors. Although this may cause symptoms, this aspect is unlikely to contribute to malnutrition. In addition, we assess the potential changes in the gut microbiome and how this may interact with the immune system in the process of ‘inflamm-ageing’. We conclude by summarising the main changes and their impact for the clinician along with recommendations for future areas of research.
A search for pulsars in the central parsecs of the Galactic center
- Andrew Siemion, Matthew Bailes, Geoff Bower, Jayanth Chennamangalam, Jim Cordes, Paul Demorest, Julia Deneva, Gregory Desvignes, John Ford, Dale Frail, Glenn Jones, Michael Kramer, Joseph Lazio, Duncan Lorimer, Maura McLaughlin, Scott Ransom, Anish Roshi, Mark Wagner, Dan Werthimer, Robert Wharton
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- Journal:
- Proceedings of the International Astronomical Union / Volume 8 / Issue S291 / August 2012
- Published online by Cambridge University Press:
- 20 March 2013, p. 57
- Print publication:
- August 2012
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The discovery of a pulsar or pulsars orbiting near the Galactic Center (GC) could offer an unprecedented probe of strong-field gravity, the properties of our galaxy's supermassive black hole and insights into the paradoxical star formation history of the region. However, searching for pulsars near the GC is severely hampered by the large electron densities along our line of sight and the scattering-induced pulse broadening of the pulsar emission observed through it. As the broadened pulse length approaches the pulsar period, the periodicity in pulsar emission becomes nearly undetectable. Searches extended to higher frequencies, in an effort to reduce scattering, suffer from reduced intrinsic flux, higher system temperatures and increased atmospheric opacity. We are currently attempting to mitigate the challenges associated with searching for pulsars near the GC by employing new wide bandwidth receivers, upgraded IF distribution systems and novel digital spectrometers in a GC pulsar search campaign at the Green Bank Telescope in West Virginia, USA.
Our search will cover two frequency bands, from 12-15 GHz (Ku Band) and 18-26 GHz (K Band), during a total of approximately 30 hours of observations, with expected characteristic 10-sigma sensitivities between 5-10 micro-Jy. Our first observations are scheduled for mid-March 2012. Here we will present the status of our observations and initial results.